The following articles cover important research around coronavirus immunity. This research has potential implications for vaccine design, therapeutic development as well as new ways to diagnose infection.
Angkana T. Huang et al. released a pre-print review of antibody-mediated immunity to coronaviruses, including SARS-CoV-2, SARS-CoV-1, MERS-CoV and human endemic coronaviruses. Research from other coronaviruses may provide clues to SARS-CoV-2 immunity and help guide both research and policy-making.
A pre-print article by de Assis et al. describes the validation of a SARS-CoV-2-specific antigen microarray using convalescent plasma. The test demonstrated low cross-reactivity with antibodies from other coronaviruses and offers potential as both a diagnostic tool and a research resource to estimate disease burden and correlate antibody responses with clinical outcomes.