Ofer Levy, M.D., Ph.D.

Havard Medical School

About Ofer Levy, M.D., Ph.D.

Ofer Levy MD, PhD, brings precision medicine principles to vaccine research. He does this by building collaborative, multi-disciplinary international teams that create innovative vaccines tailored to the specific needs of vulnerable populations. Together with his colleagues, he has developed unique, blood-based systems that enable study of human immunity outside the body. Using these tools, the team discovered that the human immune system changes markedly with age, revealing the need to develop vaccines optimized to protect specific populations at high risk of infection such as the very young or older adults. Dr. Levy is the Director of the Precision Vaccines Program, staff physician in the Division of Infectious Diseases at Boston Children’s Hospital and Professor of Pediatrics at Harvard Medical School in Boston, MA. He is currently leading an NIH/NIAID-funded Human Immunology Project Consortium center, which is working to define molecular mechanisms of vaccine protection in infants across the globe, including West Africa and Australasia. His research projects also include NIH- and Gates foundation-supported discovery and development of adjuvants, small molecules that boost immune responses and can be used to create age-specific vaccines. Dr. Levy and the Precision Vaccines Network are now working on adjuvant-boosted vaccines to provide protection against COVID-19, influenza, pertussis (whooping cough), HIV, and opioid use disorder/overdose. A member of the U.S. FDA coronavirus vaccine advisory committee, he has authored of over 150 peer-reviewed scientific articles in journals such as Science Translational Medicine, Nature Reviews Immunology and Immunity. He has given multiple TED/TEDx talks and his work has been featured on news outlets such as CNN, FOXBusiness News, NBC Nightly News, BBC World Service, The Boston Globe, The New York Times, The Wall Street Journal, USA Today, The Washington Post, National Geographic and Scientific American.