Barney Graham, M.D., Ph.D., is an immunologist, virologist and clinical trials physician whose primary interests are viral pathogenesis, immunity and vaccine development. His work is focused on respiratory syncytial virus (major cause of bronchiolitis and pneumonia in young children), influenza, coronaviruses, HIV and other emerging viral diseases.
After graduating from Rice University, he obtained his M.D. from the University of Kansas School of Medicine in 1979. He then completed residency and two chief residencies in internal medicine, a fellowship in infectious diseases, and a Ph.D. in microbiology and immunology at Vanderbilt University School of Medicine, Nashville, Tenn. At Vanderbilt, he rose to the rank of professor of medicine with a joint appointment in the Department of Microbiology & Immunology.
In 2000, Graham became one of the founding investigators for the National Institute of Allergy and Infectious Diseases’ (NIAID) Vaccine Research Center (VRC) at the National Institutes of Health (NIH), where he is now the deputy director and chief of the Viral Pathogenesis Laboratory. He oversees the advanced development of VRC candidate vaccine products.
Graham serves as a consultant for organizations involved in vaccine development for HIV, tuberculosis, malaria, respiratory syncytial virus and emerging viral pathogens. His laboratory investigates basic mechanisms by which T-cells affect viral clearance and immunopathology, explores mechanisms of antibody-mediated viral neutralization, and develops vaccine approaches for respiratory virus infections and emerging viral diseases.