Vaccines lead to a drastic decline in devastating diseases, disability, inequity and death worldwide. Many of us are here today because we or previous generations were vaccinated. But vaccine research is increasingly held back by the limits of scientific knowledge.
Today, the diseases we battle are much more insidious and biologically complex than those conquered in the past. Despite decades of work and billions in investment, vaccines for HIV, tuberculosis, and cancers have evaded scientists’ best efforts and humanity remains unprepared against the next pandemic.
A new approach is necessary now, one that is rooted in identifying and understanding the common elements of the human immune system that overlap across global populations and that allows us to harness this knowledge and the collective intelligence of scientists worldwide toward prevention and control of a range of diseases.