Pioneering a New Era in Human Health

For the first time ever, scientists at the Human Vaccines Project are combining systems biology with artificial intelligence to understand one of the greatest remaining frontiers of human health, the human immune system.

Modeled after the transformative Human Genome Project, the Human Vaccines Project is leveraging cutting-edge technologies to decode the human immune system. Our scientists are working to unlock new preventions, diagnostics, and treatments for some of the world’s most devastating diseases.


Vaccines that harness the human immune system already have added decades to our lives. They have helped people conquer and control a wide range of diseases, but humanity is increasingly held back by the limits of scientific knowledge.

Today, the diseases people battle are much more insidious and biologically complex than those conquered in the past. Despite decades of work and billions in investment, vaccines for HIV, tuberculosis, and cancers have evaded scientists’ best efforts and humanity remains unprepared against the next pandemic.

A new approach is necessary now, one that is rooted in identifying and understanding the common elements of the human immune system that overlap across global populations and that allows us to harness this knowledge and the collective intelligence of scientists worldwide toward prevention and control of a range of diseases.


At the Human Vaccines Project, we are taking an entirely new approach to fighting disease. We are harnessing the power of the human immune system with the enormous potential of machine learning and artificial intelligence, to decipher the key principles guiding human immunity across diseases.

Through our innovative business model and global consortium, the Human Vaccines Project is putting these technologies in the hands of the world’s top scientists.


Our goal is nothing short of enabling people to live much healthier — and longer — lives.

The immune system — an intricate network of cells, tissues, and organs — is the human body’s primary mechanism for staying healthy. Decoding it should be central to our efforts to understand and fight disease, whether non-communicable diseases such as cancer, diabetes, and Alzheimer’s, or infectious ones such as tuberculosis, malaria, and Ebola. We see a world in which:

  • Immunotherapies for cancer worked for all cancers in all cancer patients
  • Vaccines are effective for life, in all populations
  • Alzheimer’s disease is preventable
  • The next flu pandemic, or other emerging threat, could be avoided

We are working to make disease prevention, diagnosis, and treatment effective for all people, across all diseases.


In 2014, 35 of the world’s leading scientists called for the creation of a decade-long, multi-billion dollar initiative to decode the human immune system. Modeled after the Human Genome Project, which has transformed biomedical research, the Human Vaccines Project is seeking to transform how we fight our most devastating disease by unlocking the mechanisms of human immunity — accelerating the development of new vaccines, diagnostics, and treatments.